Evaluation of the Afinion AS100 Point-of-Care Analyzer for Hemoglobin A1c
نویسنده
چکیده
An evaluation of a new Afinion AS100 Analyzer was conducted to assess analytical performance. Precision was estimated by analyzing 2 control and 3 patient samples twice a day for 10 days. Accuracy was established by analysis of 6 samples from the National Glycated Hemoglobin Standardization Program for a 3-day period. Agreement was correlated to a laboratory method, the Variant II Turbo Hemoglobin Testing System, and a point-of-care method, the DCA2000+ Hemoglobin A1c System, using leftover EDTA samples from laboratory analysis (n = 110, range of results = 4.6%Y13.7% HbA1c). The Afinion AS100 Analyzer (0.9%Y1.8% coefficient of variation [CV]) displayed laboratory comparable precision (Variant II Turbo = 1.1%Y1.9% CV) that was superior to the DCA2000+ (2.9%Y3.3% CV) with minimal bias to the National Glycated Hemoglobin Standardization Program target concentrations (G0.2% HbA1c average unit bias or 3.1%). The Afinion AS100 Analyzer had good agreement with both the Variant II Turbo and DCA2000+ with r of greater than 0.9837 and Sy.x of T0.22% and T0.29% HbA1c, respectively. Staff found the analyzer easy to train and use, providing faster results than the DCA2000+ (3 minutes vs 6 minutes). The Afinion AS100 Analyzer will be recommended over the DCA2000+ when requests for future point-of-care HbA1c are made in our health system.
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